Immune signaling
Thymosin Alpha-1
Also known as Talpha1, Zadaxin
28 residues, N-terminally acetylated · 3018.37 g/mol
A 28-residue thymic peptide studied for Toll-like-receptor signaling and T-cell maturation in immune research.
Originally purified from thymic tissue, thymosin alpha-1 participates in T-lymphocyte maturation. Published work describes signaling through Toll-like receptors, principally TLR2 and TLR9, on dendritic cells and monocytes, with MyD88-dependent activation driving downstream cytokine programs. It is a common reference standard in innate-immunity and vaccine-adjuvant research, and is distinct from the beta-series thymosins such as thymosin beta-4.
Common research areas
- TLR2 / TLR9 activation assays
- Dendritic-cell maturation
- Th1 / Th2 polarization panels
In our catalog
Thymosin Alpha-1 10 mg · $95 CAD · ≥99% HPLC
Related compounds
Selected references
- 1. Aging and Thymosin Alpha-1. Int J Mol Sci, 2025. PMID 41373628
- 2. Thymosin alpha-1. Am J Health Syst Pharm, 2001. PMID 11381492
- 3. beta-Thymosins. Ann N Y Acad Sci, 2007. PMID 17468232
For laboratory research use only. Reference information, not usage guidance or dosing advice.