Metabolic research

5-Amino-1MQ: NNMT-inhibition research overview

Published 2026-06-18 · Pure North Peptides Editorial · Canada

A research overview of 5-Amino-1MQ, a small-molecule NNMT inhibitor studied in metabolic and NAD+ pathways, with handling and verification notes for Canadian research labs.

5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), studied for its place in metabolic and NAD+-related pathways. It is not a peptide, but it shows up in the same research programs, so it warrants the same sourcing discipline.

What NNMT inhibition is about

NNMT consumes methyl groups and influences the cellular NAD+ pool. 5-Amino-1MQ is studied as a tool compound for probing that enzyme in metabolic models. Research interest connects it to the broader NAD+ literature, see our NAD+ research overview for adjacent context.

Small molecule, same verification bar

A small molecule still needs identity and purity confirmation, the questions don't change just because it isn't a peptide. Look for an HPLC purity figure and a mass-spec identity confirmation on the lot COA. Pure North applies the same published 99% purity floor and Janoshik verification, archived at /lab-results/.

Handling and storage

Store dry and cold per the lot COA, and dissolve in the carrier solvent your protocol specifies, small molecules often differ from peptides in solubility, so check our carrier solvent reference before reconstituting. Aliquot stock solutions and minimize freeze-thaw cycling.

Verify the lot

Match the vial lot number to the COA and cross-check it against the public archive at /coa-verify/. A supplier that publishes every past lot lets you do that check independently.

Sourcing in Canada

Canadian-based and shipped domestic via Canada Post Xpresspost, dispatched within 24-48 hours, ~4 days transit, free over $200 CAD. Browse the catalog. Supplied as a reference standard for laboratory research use only.

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