Skip to content
Home / Blog / Article
Metabolic research

5-Amino-1MQ: NNMT-inhibition research overview

A research overview of 5-Amino-1MQ, a small-molecule NNMT inhibitor studied in metabolic and NAD+ pathways, with handling and verification notes for Canadian labs.

2 min readPure North Editorial · standards
Editorial laboratory scene for 5-Amino-1MQ: NNMT-inhibition research overview

5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), studied for its place in metabolic and NAD+-related pathways. It is not a peptide, but it shows up in the same research programs, so it warrants the same sourcing discipline.

What NNMT inhibition is about

NNMT consumes methyl groups and influences the cellular NAD+ pool. 5-Amino-1MQ is studied as a tool compound for probing that enzyme in metabolic models. Research interest connects it to the broader NAD+ literature, see our NAD+ research overview for adjacent context.

Small molecule, same verification bar

Pure North commissioned Canada Peptide Testing, as a paying client. Published reports cover RP-HPLC-UV area purity and measured content for named samples and vial sizes. They do not include mass-spectrometry identity, endotoxin, sterility or water-content results. Read the original documents at Lab Results. No published report is currently listed for 5-Amino-1MQ.

Handling and storage

Store dry and cold per the lot COA, and dissolve in the carrier solvent your protocol specifies, small molecules often differ from peptides in solubility, so check our carrier solvent reference before reconstituting. Aliquot stock solutions and minimize freeze-thaw cycling.

Verify the lot

Match the vial lot number to the COA and cross-check it against the lot archive at /coa-verify/, then ask customer service for that lot’s signed certificate. A supplier that can produce every past lot’s document lets you do that check independently.

Sourcing in Canada

Canadian-based and shipped domestic via Canada Post Xpresspost, dispatched within 24-48 hours, ~4 days transit, free over $300 CAD. Browse the catalog. Supplied as a reference standard for laboratory research use only.

Continue reading

For laboratory research use only. Reference information, not medical advice or human-use guidance.

Compounds in this article
Continue reading