Anxiolytic / neuroimmune signaling
Selank
Also known as Tuftsin analog TP-7
Thr-Lys-Pro-Arg-Pro-Gly-Pro · 751.88 g/mol
A synthetic tuftsin analog extended with Pro-Gly-Pro, studied for GABAergic and neuroimmune signaling.
Selank is built on the immunomodulatory tetrapeptide tuftsin with the same Pro-Gly-Pro stabilising tail used in Semax. Published work describes modulation of GABA-A receptor expression and inhibition of enkephalin-degrading enzymes, which stabilises endogenous enkephalin levels. Its tuftsin backbone also gives it documented effects on interleukin expression, which is why it appears in both the anxiolytic and the neuroimmune literature.
Common research areas
- GABA-A receptor expression
- Enkephalin stability studies
- Interleukin expression panels
In our catalog
Selank 10 mg · $55 CAD · ≥99% HPLC
Related compounds
Selected references
- 1. Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats. Bull Exp Biol Med, 2022. PMID 36322304
- 2. Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats. Bull Exp Biol Med, 2019. PMID 31625062
- 3. [Effects of heptapeptide selank on genetically-based and situation-provoked symptoms of depression in behavior in WAG/Rij and Wistar rats, and in BALB/c mice]. Zh Vyssh Nerv Deiat Im I P Pavlova, 2008. PMID 18661785
For laboratory research use only. Reference information, not usage guidance or dosing advice.