Endotoxin testing and HPLC answer different questions

What the absence of an endotoxin result means when reading Pure North’s published HPLC-UV reports.

An HPLC purity result is not an endotoxin result

Endotoxin testing is a separate analytical question. A high HPLC area-purity figure does not establish that a material is endotoxin-free or suitable for a particular biological assay.

Pure North commissioned Canada Peptide Testing, as a paying client. Published reports cover RP-HPLC-UV area purity and measured content for named samples and vial sizes. They do not include mass-spectrometry identity, endotoxin, sterility or water-content results. Read the original documents at Lab Results.

What Pure North currently publishes

The published CPT set does not contain an endotoxin assay. This page previously stated release limits and availability of low-endotoxin lots that the published evidence did not support. Those statements have been removed. Do not interpret an omitted test as a passing result.

Plan the required evidence before ordering

If endotoxin status matters to your research, ask a qualified analytical laboratory about a suitable method, sample requirements, detection limits and interference controls. Acceptance criteria should come from the validated research method rather than a universal supplier claim.

Manufacturer QC documents are a separate evidence source and may be available for other peptide lots. Read the actual document for its scope; do not transfer a result from one sample or document to another.

Read the complete certificate

Match the compound, vial size and lot or assigned reference before relying on a report. If a reference differs from the vial label, contact purenorthpeptides@proton.me for the documented connection. A report does not cover another size or future lot.

See how to read a peptide COA for area purity, measured content and report matching.

For laboratory research use only. Published analytical results do not establish clinical safety or Health Canada or FDA approval.