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SS-31 (elamipretide) and cardiolipin, mitochondrial protection mechanism

Why this tetrapeptide accumulates 5,000× in mitochondria and what it means for mitochondrial-disease research models.

2 min readPure North Editorial · standards
Editorial laboratory scene for SS-31 (elamipretide) and cardiolipin, mitochondrial protection mechanism

In a Canadian research-peptide context, SS-31 sits within the longevity class of reference standards. This post collects what HPLC-verified labs need to source, store, and reproducibly use this material, drawn from public literature and Pure North's reference-standard handling practices.

Why SS-31 matters

Pure North publishes laboratory reports for the samples and vial sizes listed in Lab Results. Each report identifies its method, reference, area purity and measured content. Open the matching product page to check coverage for the size you select. A report does not cover every size or future lot; contact customer service if your vial reference differs. Bacteriostatic water has no COA.

The protocol short-version

For Canadian research labs working with SS-31, the lifecycle is: on receiving the lyophilized vial, transfer it immediately to a research-grade −20 °C freezer, reconstitute in sterile bacteriostatic water at the working concentration your protocol specifies, and use within a validated, material-specific stability window. Avoid repeated freeze-thaw cycles, the effect depends on the material and handling conditions.

Cross-batch reproducibility

Match the compound, vial size and lot or assigned reference before relying on a report. If a reference differs from the vial label, contact purenorthpeptides@proton.me for the documented connection. A report does not cover another size or future lot. Keep the original report and research records when investigating unexpected results; a published COA does not establish a retain-sample programme.

Where to source it in Canada

SS-31 10 mg is stocked by Pure North Peptides. For the reference standards Pure North does carry, the company is Canadian-based and ships across Canada via Canada Post Xpresspost, orders are dispatched within 24-48 hours, with typical transit around 4 days. Browse the available catalog at /products/. Read more on storage and handling in our storage guide, on dispatch and transit in our shipping policy, lot verification at /coa-verify/, or the public lot archive at /lab-results/.

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For laboratory research use only. Reference information, not medical advice or human-use guidance.

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