Is Ipamorelin from Pure North Peptides HPLC verified?

Yes. Every Ipamorelin lot Pure North Peptides ships is HPLC-purity tested at synthesis and retested by Janoshik Analytical before release. The lot-specific Certificate of Analysis is published on the Lab Results page.

How is Ipamorelin shipped?

Ipamorelin is lyophilized at synthesis, sealed under nitrogen, and shipped across Canada via Canada Post Xpresspost in ~4 days. Free shipping over $250 CAD. ~4 days transit Canada-wide.

Where can I see the COA for Ipamorelin?

Lot-specific Certificate of Analysis available on request — email purenorthpeptides@proton.me with the lot/batch number from your order confirmation and we'll send it for your records.

What does HPLC-verified mean?

Every lot we sell is tested by an independent third-party lab (Janoshik Analytical) using High-Performance Liquid Chromatography. The Certificate of Analysis reports purity, peptide content by mass, and identity. We post the COA next to each product so you can verify before ordering.

How is it shipped within Canada?

Canada Post Xpresspost. Most provinces arrive in ~4 days from dispatch. Free shipping on Canadian orders over $250; otherwise a flat $25 shipping fee applies.

Is this for human or animal use?

All Pure North products are supplied strictly for laboratory research use only — in-vitro reference standards. By ordering you confirm you have read and accept our Research Use Declaration.

Interac e-Transfer from any Canadian bank, or self-custodial cryptocurrency (Bitcoin, Ethereum, USDT, Monero) sent directly to our wallet — no third-party processor, no chargebacks. All prices are in CAD.

Home / Catalog / Growth Axis / Ipamorelin 10 mg

Growth axis · Selective GH secretagogue

Ipamorelin

SKU LUM-IPA-5 · C₃₈H₄₉N₉O₅ · 711.86 g/mol · CAS 170851-70-4

A selective ghrelin-receptor (GHS-R1a) agonist studied for pulsatile growth-hormone release without ACTH or cortisol cross-activation.

Purity (HPLC): ≥ 99.21%
Net peptide: 5.00 mg ± 2%
Endotoxin: < 0.5 EU/mg
Format: Lyophilized vial
Storage: −20 °C, desiccated
Shelf life: 24 months from MFG

$30CAD / 10 mg vial

In stock · Lot LM-2641

Add $250 for Free shipping

Third-party COA on fileCocer lab · HPLC ≥ 99% · Janoshik verified — view report →

HPLC + MS verified per lot
~4 days to your door
COA bundled with shipment
Lot samples retained 5 years

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Overview

Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH₂) that selectively activates the growth-hormone secretagogue receptor (GHS-R1a) without measurable activity at receptors associated with cortisol, prolactin, or ACTH release. This selectivity is the experimental signature distinguishing it from earlier secretagogues such as GHRP-2 and GHRP-6.

Each vial is lyophilized from acetate buffer, sealed under nitrogen, and shipped ~4 days from our lab.

Research applications

GHS-R1a binding affinity and selectivity screens, pituitary GH-release assays, and comparative pharmacokinetics versus GHRP-2/GHRP-6 and natural ghrelin.

Sold for laboratory research only. This material is not a drug, food, or cosmetic and is not intended for diagnostic, therapeutic, or recreational use.

Identity

Parameter	Value
Sequence	Aib-His-D-2-Nal-D-Phe-Lys-NH₂
Molecular formula	C₃₈H₄₉N₉O₅
Molecular weight	711.86 g/mol
CAS number	170851-70-4
Length	5 residues

Quality

Test	Specification
HPLC purity	99.780%
Mass confirmation	ESI-MS within 0.5 Da
Net peptide content	≥ 80% by AAA
Endotoxin	< 0.5 EU/mg (LAL)
Bioburden	< 10 CFU/g
Residual TFA	< 1.0%

Lot LM-2641

Manufactured 04 Mar 2026 · Released 11 Mar 2026 · Tested by Pure North QC, Canada. Retain samples held under storage spec for five years from release date.

Verification

Method	Result
RP-HPLC at 220 nm	99.41% main peak
ESI-MS (positive)	711.9 Da (theor. 711.86)
Amino acid analysis	82.1% net peptide
LAL endotoxin	< 0.05 EU/mg
Karl Fischer (water)	2.8% w/w

Reconstitution

Allow vial to reach room temperature before opening (≥ 20 minutes). Reconstitute with 1.0–2.5 mL of sterile bacteriostatic water (0.9% benzyl alcohol). Inject solvent slowly down the inner wall of the vial; do not direct stream onto the lyophilized cake.

Swirl gently for 30 seconds. Do not vortex. Allow to dissolve for 5 minutes; clarity should be complete with no visible particulates.

Storage after reconstitution

Reconstituted solution is stable for 28 days at 2–8 °C in original vial. For longer storage, aliquot into low-binding tubes and hold at −80 °C; avoid repeated freeze-thaw cycles. Discard if turbidity, color change, or particulate matter is observed.

Selected references

Raun K et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552–561.

Howard AD et al. A receptor in pituitary and hypothalamus that functions in GH release. Science. 1996;273(5277):974–977.

Smith RG. Development of growth hormone secretagogues. Endocr Rev. 2005;26(3):346–360.

Citing this material

Ipamorelin reference standard, ≥99% (HPLC), Pure North Peptides Inc., Cat. No. LUM-IPA-5, Lot LM-2641.

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